Teaching in population pharmacometrics
  
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Software
The uppsala pharmacometrics groups is involved in creating software that can be used for building and using population pharmacometric models. All of our software is freely available (freeware).
 
PsN_Logo Perl-speaks-NONMEM (PsN)is a collection of Perl modules and programs aiding in the development of non-linear mixed effect models using NONMEM. The functionality ranges from simpler tasks such as parameter estimate extraction from output files, data file sub setting and resampling, to advanced computer-intensive statistical methods. PsN includes both stand-alone tools as well as development libraries for method developers.  PsN is freely available at psn.sf.net.
   
xpose_logo Xpose is a model building aid for population analysis using NONMEM. Xpose produces various plots and analyses to facilitate data set checkout, goodness-of-fit analysis, model exploration and visualization, model diagnostics, candidate covariate identification and model comparison.  Xpose 4 is written in the programming language R with a modular and object oriented design and allows for integration into nearly any model building platform.  New functionality in Xpose 4 allows the user to create simulation based reference diagnostics, create visual and numerical predictive check plots, compute the conditional weighted residuals and modify standard Xpose graphics to create publication quality figures.  Xpose is freely available at xpose.sf.net.
   
PopED 2poped

 

 PopED (Population Experimental Design) is a software tool for computing optimal experimental designs. The software has been developed with an emphasis on drug trials based on population models (non-linear mixed effects models).  PopED is freely available at andrewhooker.github.io/PopED/.